How to flush Cialis out of your system?

Cialis works much longer than other erectile dysfunction drugs like Viagra; Cialis keeps working for up to 36 hours. It is naturally eliminated by your kidneys Cialis (Tadalafil) has a long-lasting effect when compared to other phosphodiesterase (PDE-5) inhibitor drugs. This med treats erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). After you take Cialis, it blends with your blood. It soon starts to block an enzyme called phosphodiesterase type 5 (PDE5). 

When Cialis stops this enzyme, your blood vessels relax. This action helps boost blood flow and make men get an erection. 

But how does your body get rid of Cialis? 

After Cialis completes the intended action, your body begins breaking it down and eliminating the drug through the kidneys. The liver works in metabolizing the drug, using an enzyme, Cytochrome P450 3A4 (CYP3A4), to transform Cialis into inactive compounds so your body removes them.  

Once metabolized, these compounds are excreted through your digestive system, with about 61% leaving through stools and ~36% excreted via urine. However, complete clearance requires ~ five half-lives; this is nearly 96 hours (or about 4 days) for your body to fully eliminate Cialis. 

How to flush Cialis out of your system? 

No magical tricks can flush Cialis out of your system, but a few lifestyle changes can support your body’s natural detox process. Some tips to help you are below:

• Drink more water: Drinking 8–10 glasses of water a day can help kidneys work best and let go of this drug faster. 

• Get moving: When you exercise, it helps your blood flow turn better and speeds up your rate of metabolism. A faster rate of metabolism helps your body rid itself of drugs like Cialis quickly. Activities like walking fast, running, or biking can keep you healthy and also help clear drugs from your system sooner. 

• Eat well: The Foods you eat affect how your liver works. Eating foods with antioxidants and fibers—think green leafy veggies, berries, apples, broccoli, and whole grains—can help keep your liver and digestion healthy. 

• Stay away from alcohol and grapefruit juice: Alcohol and grapefruit (or its juice) can mess with how your body breaks down Cialis. Grapefruit juice can block liver enzymes processing tadalafil; this can make the drugs to hang around in your system longer. 

For what duration does Cialis stay in the body? 

“Half-life” describes how long it takes for your body to flush out medications. Cialis influences the body much longer than many other erectile dysfunction (ED) drugs. Its extended effects stem from its stretched half-life, which lasts ~ 17.5 hours. 

This means after 17.5 hours, 50% of a dose remains in the blood, and after 35 hours, 25% remains active. Most of the drug is cleared from the body in 3 to 4 days. In comparison, Viagra (i.e., sildenafil) leaves your system faster; with a half-life of 4 – 5 hours, your body clears Viagra in less than a day.  

But Cialis tends to have its effects felt for up to 36 hours; this earns it the nickname “weekend pill”. This med lets you have spontaneous intimate moments for 2 days i.e., without needing another dose.  

Factors influencing how long Cialis stays in your body 

In case of many adults, Cialis clears out on its own within a few days. But still, there are some factors influencing how long Cialis remains in. These include your age, how well your liver is, your renal health, how fast your body processes drugs, and other pills you are taking—if any. 

Of these, age has a bigger impact on how soon your body processes Cialis and gets rid of it. As you turn old, your body starts slowing down – with liver / kidneys working at a slower pace. If you have liver or kidney problems, it is going to take longer to process this drug.  
 
A few drugs may have an impact on how Cialis breaks-down. Meds affecting liver enzymes – such as antibiotics, antifungals, and a few HIV drugs can change how your body processes Cialis. Additionally, some drugs may boost Cialis level in blood; this leads to long-lasting effects. It is hence an important thing to tell your doctor of any medicines you are taking now. 

As such, there is no quicker ways to get Cialis out. But you your body naturally cleanse by drinking plenty of water, exercising often, eating healthier foods, and staying away from alcohol, grapefruit juice, etc. 

Dr.Ashley

Dr. Ashley, is a clinical pharmacist and certified medical content specialist with a focus on men’s health, pharmacology, and sexual wellness. With over a decade of experience in patient education.